Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection

Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection

Abstract The SARS-CoV-2 Omicron variant evades most currently approved neutralizing antibodies (nAbs) and caused drastic decrease of plasma neutralizing activity elicited by vaccination or prior infection, urging the need for the development of pan-variant antivirals. Breakthrough infection induces...

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Bibliographic Details
Main Authors: Yu Guo, Guangshun Zhang, Qi Yang, Xiaowei Xie, Yang Lu, Xuelian Cheng, Hui Wang, Jingxi Liang, Jielin Tang, Yuxin Gao, Hang Shang, Jun Dai, Yongxia Shi, Jiaxi Zhou, Jun Zhou, Hangtian Guo, Haitao Yang, Jianwei Qi, Lijun Liu, Shihui Ma, Biao Zhang, Qianyu Huo, Yi Xie, Junping Wu, Fang Dong, Song Zhang, Zhiyong Lou, Yan Gao, Zidan Song, Wenming Wang, Zixian Sun, Xiaoming Yang, Dongsheng Xiong, Fengjiang Liu, Xinwen Chen, Ping Zhu, Ximo Wang, Tao Cheng, Zihe Rao
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39267-x

Internet

https://doi.org/10.1038/s41467-023-39267-x

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