Pathologically expanded peripheral CD4+PD‐1+Foxp3− T‐cell subset promotes B‐cell hyperactivity in patients with rheumatoid arthritis

Pathologically expanded peripheral CD4+PD‐1+Foxp3− T‐cell subset promotes B‐cell hyperactivity in patients with rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is an autoimmune disease characterized by destructive polyarthritis, and abnormal T–B‐cell interactions may contribute to its pathogenesis. This study aimed to investigate the characteristics and roles of CD4+ programmed death 1 (PD‐1)+Foxp3− T cells in...

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Bibliographic Details
Main Authors: Ziran Bai, Rui Liu, Jiaqing Liu, Cheng Zhang, Zilong Wang, Jingjing Qi, Yawei Tang, Xia Li
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Rheumatology & Autoimmunity
Subjects:
B‐cell hyperactivity
CD4+PD‐1+Foxp3− T cells
rheumatoid arthritis
type 2 helper T cells
Online Access:https://doi.org/10.1002/rai2.12114

Internet

https://doi.org/10.1002/rai2.12114

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