A novel system for the launch of alphavirus RNA synthesis reveals a role for the Imd pathway in arthropod antiviral response.

Alphaviruses are RNA viruses transmitted between vertebrate hosts by arthropod vectors, primarily mosquitoes. How arthropods counteract alphaviruses or viruses per se is not very well understood. Drosophila melanogaster is a powerful model system for studying innate immunity against bacterial and fu...

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Bibliographic Details
Main Authors: Vasanthi Avadhanula, Brandon P Weasner, Gail G Hardy, Justin P Kumar, Richard W Hardy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2738967?pdf=render