New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus

New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus

An effective vaccine against group A streptococcus (GAS) is highly desirable for definitive control of GAS infections. In the present study, two variants of amphiphilic chitosan nanoparticles-based GAS vaccines were developed. The vaccines were primarily composed of encapsulated KLH protein (a sourc...

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Bibliographic Details
Main Authors: Abdin Shakirin Mohamad Norpi, Muhammad Luqman Nordin, Nuraziemah Ahmad, Haliza Katas, Abdullah Al-Hadi Ahmad Fuaad, Asif Sukri, Nirmal Marasini, Fazren Azmi
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Amphiphilic chitosan nanoparticles
Peptide vaccine
Lipidation
Multi-adjuvanting delivery system
Immunogenicity
Group A streptococcus
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087622000435

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http://www.sciencedirect.com/science/article/pii/S1818087622000435

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