Identification of Proteins Required for Precise Positioning of Apc2 in Dendrites

In Drosophila neurons, uniform minus-end-out polarity in dendrites is maintained in part by kinesin-2-mediated steering of growing microtubules at branch points. Apc links the kinesin motor to growing microtubule plus ends and Apc2 recruits Apc to branch points where it functions. Because Apc2 acts...

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Bibliographic Details
Main Authors: Alexis T. Weiner, Dylan Y. Seebold, Nick L. Michael, Michelle Guignet, Chengye Feng, Brandon Follick, Brandon A. Yusko, Nathan P. Wasilko, Pedro Torres-Gutierrez, Melissa M. Rolls
Format: Article
Language:English
Published: Oxford University Press 2018-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200205