Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli

Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli

Acrolein is a metabolite of cyclophosphamide (CYP), an alkylating agent used for a wide range of benign and malignant diseases. CYP treatments are known to trigger hemorrhagic cystitis in patients and animals. Significant effort has been made to prevent CYP/acrolein-induced cystitis, while still mai...

Full description

Bibliographic Details
Main Authors: Sanghee Lee, Jiwoo Lee, Chandresh Khimji, Jaebeom Lee, Shelle Malkmus, Michael Albo, Tony Yaksh, George Chiang
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
acrolein
cyclophosphamide (CYP)
repeated low-dose acrolein model
urinary bladder
voiding dysfunction
Online Access:https://www.mdpi.com/2073-4409/10/12/3477

Internet

https://www.mdpi.com/2073-4409/10/12/3477

Similar Items