Altered Mitochondrial Morphology and Bioenergetics in a New Yeast Model Expressing Aβ42

Altered Mitochondrial Morphology and Bioenergetics in a New Yeast Model Expressing Aβ42

Alzheimer’s disease (AD) is an incurable, age-related neurological disorder, the most common form of dementia. Considering that AD is a multifactorial complex disease, simplified experimental models are required for its analysis. For this purpose, genetically modified <i>Yarrowia lipolytica<...

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Bibliographic Details
Main Authors: Khoren K. Epremyan, Anton G. Rogov, Tatyana N. Goleva, Svetlana V. Lavrushkina, Roman A. Zinovkin, Renata A. Zvyagilskaya
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
Aβ42
heterologous expression
yeast
<i>Yarrowia lipolytica</i>
cell death
Online Access:https://www.mdpi.com/1422-0067/24/2/900

Internet

https://www.mdpi.com/1422-0067/24/2/900

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