EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

Reticulocalbin 1 (RCN1) is an endoplasmic reticulum (ER)-residing protein, involved in promoting cell survival during pathophysiological conditions that lead to ER stress. However, the key upstream receptor tyrosine kinase that regulates RCN1 expression and its potential role in cell survival in the...

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Bibliographic Details
Main Authors: Juliana Gomez, Zammam Areeb, Sarah F. Stuart, Hong P. T. Nguyen, Lucia Paradiso, Ahmad Zulkifli, Sonakshi Madan, Vijay Rajagopal, Magdalene K. Montgomery, Hui K. Gan, Andrew M. Scott, Jordan Jones, Andrew H. Kaye, Andrew P. Morokoff, Rodney B. Luwor
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
EGFRvIII
RCN1
ER stress
apoptosis
glioblastoma
Online Access:https://www.mdpi.com/2072-6694/13/6/1198

Internet

https://www.mdpi.com/2072-6694/13/6/1198

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