Immune-Checkpoint Inhibitors (ICIs) in Metastatic Colorectal Cancer (mCRC) Patients beyond Microsatellite Instability

Immune-Checkpoint Inhibitors (ICIs) in Metastatic Colorectal Cancer (mCRC) Patients beyond Microsatellite Instability

Immune-checkpoint inhibitors (ICIs) showed impressive results in terms of activity and efficacy in metastatic colorectal cancer (mCRC) patients bearing tumors with deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H). Despite that microsatellite status is the major predictive...

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Bibliographic Details
Main Authors: Beatrice Borelli, Carlotta Antoniotti, Martina Carullo, Marco Maria Germani, Veronica Conca, Gianluca Masi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
immune-checkpoint inhibitors
deficient mismatch repair
high microsatellite instability
<i>POLE</i> mutation
metastatic colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/14/20/4974

Internet

https://www.mdpi.com/2072-6694/14/20/4974

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