An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood

An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood

Abstract Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for retention by specific body sites; therefore, they have great potential for targeted delivery of biomolecules to treat diseases. However, the pharmacokinetics and biodistribution of EVs in large animals rema...

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Bibliographic Details
Main Authors: Blanca V. Rodriguez, Yi Wen, Erin N. Shirk, Samuel Vazquez, Olesia Gololobova, Amanda Maxwell, Jessica Plunkard, Natalie Castell, Bess Carlson, Suzanne E. Queen, Jessica M. Izzi, Tom A. P. Driedonks, Kenneth W. Witwer
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Journal of Extracellular Vesicles
Subjects:
biodistribution
cell association assays
ectosomes
exosomes
Extracellular vesicles
ex vivo
Online Access:https://doi.org/10.1002/jev2.12368

Internet

https://doi.org/10.1002/jev2.12368

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