Identification of the distribution of human endogenous retroviruses K (HML-2) by PCR-based target enrichment sequencing

Abstract Background Human endogenous retroviruses (HERVs), suspected to be transposition-defective, may reshape the transcriptional network of the human genome by regulatory elements distributed in their long terminal repeats (LTRs). HERV-K (HML-2), the most preserved group with the least number of...

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Bibliographic Details
Main Authors: Bei Xue, Tiansheng Zeng, Lisha Jia, Dongsheng Yang, Stanley L. Lin, Leonardo A. Sechi, David J. Kelvin
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Retrovirology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12977-020-00519-z