Unique kinase catalytic mechanism of AceK with a single magnesium ion.

Isocitrate dehydrogenase kinase/phosphatase (AceK) is the founding member of the protein phosphorylation system in prokaryotes. Based on the novel and unique structural characteristics of AceK recently uncovered, we sought to understand its kinase reaction mechanism, along with other features involv...

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Bibliographic Details
Main Authors: Quanjie Li, Jimin Zheng, Hongwei Tan, Xichen Li, Guangju Chen, Zongchao Jia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747045?pdf=render