Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies

Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies

Abstract Tau protein aggregates in several neurodegenerative disorders, referred to as tauopathies. The tau isoforms observed in post mortem human brain aggregates is used to classify tauopathies. However, distinguishing tauopathies ante mortem remains challenging, potentially due to differences bet...

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Bibliographic Details
Main Authors: Nathalie Kyalu Ngoie Zola, Clémence Balty, Sébastien Pyr dit Ruys, Axelle A. T. Vanparys, Nicolas D. G. Huyghe, Gaëtan Herinckx, Manuel Johanns, Emilien Boyer, Pascal Kienlen-Campard, Mark H. Rider, Didier Vertommen, Bernard J. Hanseeuw
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39328-1

Internet

https://doi.org/10.1038/s41467-023-39328-1

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