Effects of Combined Admistration of Imatinib and Sorafenib in a Murine Model of Liver Fibrosis

Effects of Combined Admistration of Imatinib and Sorafenib in a Murine Model of Liver Fibrosis

Liver fibrosis is defined as excessive extracellular matrix deposition in the hepatic parenchyma as a consequence of complex interactions among matrix-producing hepatic stellate cells (HSCs) and liver-resident and infiltrating cells. In addition to the liver, the process of fibrosis may represent en...

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Bibliographic Details
Main Authors: Antonio Pesce, Rosella Ciurleo, Alessia Bramanti, Eliana Concetta Armeli Iapichino, Maria Cristina Petralia, Gaetano Giuseppe Magro, Paolo Fagone, Placido Bramanti, Ferdinando Nicoletti, Katia Mangano
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
liver fibrosis
imatinib
sorafenib
traumatic spinal cord injury
Online Access:https://www.mdpi.com/1420-3049/25/18/4310

Internet

https://www.mdpi.com/1420-3049/25/18/4310

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