Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients

Comparison of methods for donor-derived cell-free DNA quantification in plasma and urine from solid organ transplant recipients

In allograft monitoring of solid organ transplant recipients, liquid biopsy has emerged as a novel approach using quantification of donor-derived cell-free DNA (dd-cfDNA) in plasma. Despite early clinical implementation and analytical validation of techniques, direct comparisons of dd-cfDNA quantifi...

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Bibliographic Details
Main Authors: Nicholas Kueng, Séverine Arcioni, Fanny Sandberg, Christian Kuhn, Vanessa Banz, Carlo R. Largiadèr, Daniel Sidler, Ursula Amstutz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
dd-cfDNA
ddPCR
biomarker
cell-free DNA
high-throughput sequencing
liver transplant
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1089830/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1089830/full

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