Blood leukocytes from benznidazole-treated indeterminate chagas disease patients display an overall type-1-modulated cytokine profile upon short-term in vitro stimulation with <it>trypanosoma cruzi</it> antigens

Blood leukocytes from benznidazole-treated indeterminate chagas disease patients display an overall type-1-modulated cytokine profile upon short-term in vitro stimulation with <it>trypanosoma cruzi</it> antigens

<p>Abstract</p> <p>Background</p> <p>Benznidazole (Bz)-chemotherapy is recommended to prevent Chagas disease progression, despite its limited efficacy during chronic disease. However, the host mechanisms underlying these benefits still remain to be elucidated.</p>...

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Bibliographic Details
Main Authors: Sathler-Avelar Renato, Vitelli-Avelar Danielle, Elói-Santos Silvana, Gontijo Eliane, Teixeira-Carvalho Andréa, Martins-Filho Olindo
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Infectious Diseases
Subjects:
Chagas disease
Benznidazole
Immune response
Cytokines
Leucocytes subsets
CNPq
FAPEMIG
FIOCRUZ
Online Access:http://www.biomedcentral.com/1471-2334/12/123

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http://www.biomedcentral.com/1471-2334/12/123

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