New Insight on 2D In Vitro Angiogenesis Models: All That Stretches Is Not a Tube

A Matrigel-based tube formation assay is a simple and widely accepted 2D angiogenesis model in vitro. Extracellular matrix (EM) proteins and growth factors (GFs) from Matrigel<sup>TM</sup> exclusively trigger endothelial cell (EC) tubular network (ETN) formation. Co-culture of ECs with m...

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Bibliographic Details
Main Authors: Irina Beloglazova, Ekaterina Zubkova, Konstantin Dergilev, Yulia Goltseva, Yelena Parfyonova
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/20/3278