New Insight on 2D In Vitro Angiogenesis Models: All That Stretches Is Not a Tube
A Matrigel-based tube formation assay is a simple and widely accepted 2D angiogenesis model in vitro. Extracellular matrix (EM) proteins and growth factors (GFs) from Matrigel<sup>TM</sup> exclusively trigger endothelial cell (EC) tubular network (ETN) formation. Co-culture of ECs with m...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/20/3278 |