Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level

Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level

Single-cell omics aim at charting the different types and properties of all cells in the human body in health and disease. Over the past years, myriads of cellular phenotypes have been defined by methods that mostly required cells to be dissociated and removed from their original microenvironment, t...

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Bibliographic Details
Main Authors: Francesca Maria Bosisio, Yannick Van Herck, Julie Messiaen, Maddalena Maria Bolognesi, Lukas Marcelis, Matthias Van Haele, Giorgio Cattoretti, Asier Antoranz, Frederik De Smet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
multiplexed immunofluorescencence and immunohistochemistry
spatial profiling
single-cell ‘omics
tissue architecture analysis
methods for spatial profiling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.918900/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.918900/full

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