Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence

Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence

Mitochondria are one of organelles that undergo significant changes associated with senescence. An increase in mitochondrial size is observed in senescent cells, and this increase is ascribed to the accumulation of dysfunctional mitochondria that generate excessive reactive oxygen species (ROS). Suc...

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Bibliographic Details
Main Authors: Yun Haeng Lee, Ji Yun Park, Haneur Lee, Eun Seon Song, Myeong Uk Kuk, Junghyun Joo, Sekyung Oh, Hyung Wook Kwon, Joon Tae Park, Sang Chul Park
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
mitochondrial metabolic reprogramming
mitochondria
ROS
senescence amelioration
Online Access:https://www.mdpi.com/2073-4409/10/11/3003

Internet

https://www.mdpi.com/2073-4409/10/11/3003

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