p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder

p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder

T-2 toxin is an unavoidable food and feed contaminant that seriously threatens human and animal health. Exposure to T-2 toxin can cause testosterone synthesis disorder in male animals, but the molecular mechanism is still not completely clear. The MAPK pathway participates in the regulation of testo...

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Bibliographic Details
Main Authors: Xu Yang, Wenxi Song, Kefei Zhang, Youshuang Wang, Fengjuan Chen, Yunhe Chen, Tingyu Huang, Yibao Jiang, Xuebing Wang, Cong Zhang
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
T-2 toxin
Testosterone synthesis
MAPK signaling pathway
Testis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323001999

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http://www.sciencedirect.com/science/article/pii/S0147651323001999

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