Comparison between febuxostat and allopurinol uric acid-lowering therapy in patients with chronic heart failure and hyperuricemia: a multicenter randomized controlled trial

Comparison between febuxostat and allopurinol uric acid-lowering therapy in patients with chronic heart failure and hyperuricemia: a multicenter randomized controlled trial

Objective Heart failure (HF) is a common and highly morbid cardiovascular disorder. Oxidative stress worsens HF, and uric acid (UA) is a useful oxidative stress marker. The novel anti-hyperuricemic drug febuxostat is a potent non-purine selective xanthine oxidase inhibitor. The present study examine...

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Bibliographic Details
Main Authors: Satoshi Suzuki, Akiomi Yoshihisa, Tetsuro Yokokawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Akihiro Tsuda, Tatsunori Tsuda, Toshiyuki Ishibashi, Ichiro Konno, Osamu Yamaguchi, Hirofumi Machii, Naoki Nozaki, Takeshi Niizeki, Takuya Miyamoto, Yasuchika Takeishi
Format: Article
Language:English
Published: SAGE Publishing 2021-12-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211062770

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https://doi.org/10.1177/03000605211062770

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