IsomiRage: from functional classification to differential expression of miRNAs and their isoforms
As more small RNA sequencing libraries are becoming available, it clearly emerges that microRNAs (miRNAs) are highly heterogeneous both in length and sequence. In comparison to canonical miRNAs, miRNA isoforms (termed as isomiRs) might exhibit different biological properties, such as a different tar...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-09-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00038/full |