Origin and evolution of transporter substrate specificity within the NPF family

Origin and evolution of transporter substrate specificity within the NPF family

Despite vast diversity in metabolites and the matching substrate specificity of their transporters, little is known about how evolution of transporter substrate specificities is linked to emergence of substrates via evolution of biosynthetic pathways. Transporter specificity towards the recently evo...

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Bibliographic Details
Main Authors: Morten Egevang Jørgensen, Deyang Xu, Christoph Crocoll, Heidi Asschenfeldt Ernst, David Ramírez, Mohammed Saddik Motawia, Carl Erik Olsen, Osman Mirza, Hussam Hassan Nour-Eldin, Barbara Ann Halkier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
substrate specificity and electrogenicity
transporter evolution
metabolite transporters
indole glucosinolate transport
cyanogenic glucoside transport
Online Access:https://elifesciences.org/articles/19466

Internet

https://elifesciences.org/articles/19466

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