Potential role of Lu/BCAM in HIV-related atherosclerosis
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules....
| المؤلفون الرئيسيون: | , , |
|---|---|
| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
AOSIS
2019-09-01
|
| سلاسل: | African Journal of Laboratory Medicine |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ajlmonline.org/index.php/ajlm/article/view/792 |
| الملخص: | Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients. |
|---|---|
| تدمد: | 2225-2002 2225-2010 |