Whole-genome surveillance identifies markers of Plasmodium falciparum drug resistance and novel genomic regions under selection in Mozambique

Whole-genome surveillance identifies markers of Plasmodium falciparum drug resistance and novel genomic regions under selection in Mozambique

ABSTRACT The emergence of Plasmodium falciparum drug resistance threatens the efficacy of antimalarial therapies globally. Population genomic studies have been instrumental in mapping malaria genes associated with drug resistance. However, to understand the impact of regional malaria control strateg...

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Bibliographic Details
Main Authors: Erin Coonahan, Hunter Gage, Daisy Chen, Emilia Virginia Noormahomed, Titos Paulo Buene, Irina Mendes de Sousa, Kevan Akrami, Lucia Chambal, Robert T. Schooley, Elizabeth A. Winzeler, Annie N. Cowell
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Plasmodium falciparum
severe malaria
whole-genome sequencing
selective whole genome amplification
antimalarial drug resistance
genetic variation
Online Access:https://journals.asm.org/doi/10.1128/mbio.01768-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01768-23

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