The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with poor prognosis in various cancers. In recent...

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Bibliographic Details
Main Authors: Poonam Shah, Alexandre Chaumet, Stephen J. Royle, Frederic A. Bard
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/8/915