First line therapy in stage IV BRAF mutated colorectal cancer

Introduction: The molecular profile of colorectal cancer (CRC) plays a crucial role in understanding patient prognosis and treatment response. Within CRC, a distinct subgroup can be identified by the presence of the BRAF V600E mutation. This specific mutation, classified as Class I of BRAF mutations...

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Main Authors: Fausto Petrelli, Maria Antista, Lorenzo Dottorini, Alessandro Russo, Marcella Arru, Roberta Invernizzi, Mariangela Manzoni, Chiara Cremolini, Alberto Zaniboni, Ornella Garrone, Gianluca Tomasello, Michele Ghidini
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024125285