Platelet mechanosensing of collagen matrices.

During vascular injury, platelets adhere to exposed subendothelial proteins, such as collagen, on the blood vessel walls to trigger clot formation. Although the biochemical signalings of platelet-collagen interactions have been well characterized, little is known about the role microenvironmental bi...

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Bibliographic Details
Main Authors: Matthew F Kee, David R Myers, Yumiko Sakurai, Wilbur A Lam, Yongzhi Qiu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411076?pdf=render