Regulatory effects of IRF4 on immune cells in the tumor microenvironment

Regulatory effects of IRF4 on immune cells in the tumor microenvironment

The tumor microenvironment (TME) is implicated in tumorigenesis, chemoresistance, immunotherapy failure and tumor recurrence. Multiple immunosuppressive cells and soluble secreted cytokines together drive and accelerate TME disorders, T cell immunodeficiency and tumor growth. Thus, it is essential t...

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Bibliographic Details
Main Authors: Jing Lu, Taotao Liang, Ping Li, Qingsong Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
IRF4
tumor microenvironment
immunosuppressive cells
T cell exhaustion
immunoregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1086803/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1086803/full

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