Natural Phytochemicals, Luteolin and Isoginkgetin, Inhibit 3C Protease and Infection of FMDV, In Silico and In Vitro

Natural Phytochemicals, Luteolin and Isoginkgetin, Inhibit 3C Protease and Infection of FMDV, In Silico and In Vitro

Foot-and-mouth-disease virus (FMDV) is a picornavirus that causes a highly contagious disease of cloven-hoofed animals resulting in economic losses worldwide. The 3C protease (3C<sup>pro</sup>) is the main protease essential in the picornavirus life cycle, which is an attractive antivira...

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Bibliographic Details
Main Authors: Sirin Theerawatanasirikul, Nattarat Thangthamniyom, Chih-Jung Kuo, Ploypailin Semkum, Nantawan Phecharat, Penpitcha Chankeeree, Porntippa Lekcharoensuk
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Viruses
Subjects:
foot-and-mouth-disease virus (FMDV)
luteolin
isoginkgetin
phytochemicals
FMDV 3C<sup>pro</sup>
antiviral activity
Online Access:https://www.mdpi.com/1999-4915/13/11/2118

Internet

https://www.mdpi.com/1999-4915/13/11/2118

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