Serum melatonin concentration in critically ill patients randomized to sedation or non-sedation

Abstract Background Abolished circadian rhythm is associated with altered cognitive function, delirium, and as a result increased mortality in critically ill patients, especially in those who are mechanically ventilated. The causes are multifactorial, of which changes in circadian rhythmicity may pl...

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Bibliographic Details
Main Authors: Jakob Oxlund, Torben Knudsen, Thomas Strøm, Jørgen T. Lauridsen, Poul J. Jennum, Palle Toft
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:Annals of Intensive Care
Subjects:
Online Access:https://doi.org/10.1186/s13613-021-00829-1