Evaluation of the Effects of Library Preparation Procedure and Sample Characteristics on the Accuracy of Metagenomic Profiles

Metagenomic library preparation methods and sequencing technologies continue to advance rapidly, allowing researchers to characterize microbial communities in previously underexplored environmental samples and systems. However, widely accepted standardized library preparation methods can be cost-pro...

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Bibliographic Details
Main Authors: Christopher A. Gaulke, Emily R. Schmeltzer, Mark Dasenko, Brett M. Tyler, Rebecca Vega Thurber, Thomas J. Sharpton
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:mSystems
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00440-21