Whole genome sequencing identified a 16 kilobase deletion on ECA13 associated with distichiasis in Friesian horses

Whole genome sequencing identified a 16 kilobase deletion on ECA13 associated with distichiasis in Friesian horses

Abstract Background Distichiasis, an ocular disorder in which aberrant cilia (eyelashes) grow from the opening of the Meibomian glands of the eyelid, has been reported in Friesian horses. These misplaced cilia can cause discomfort, chronic keratitis, and corneal ulceration, potentially impacting vis...

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Bibliographic Details
Main Authors: E. A. Hisey, H. Hermans, Z. T. Lounsberry, F. Avila, R. A. Grahn, K. E. Knickelbein, S. A. Duward-Akhurst, M. E. McCue, T.S. Kalbfleisch, M. E. Lassaline, W. Back, R. R. Bellone
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
Genome wide association study (GWAS)
Distichiasis
Meibomian gland
Haplotype
Whole genome sequencing (WGS)
Functional annotation of animal genomes (FAANG)
Online Access:https://doi.org/10.1186/s12864-020-07265-8

Internet

https://doi.org/10.1186/s12864-020-07265-8

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