The dynamics of naturally acquired immunity to Plasmodium falciparum infection.

Severe malaria occurs predominantly in young children and immunity to clinical disease is associated with cumulative exposure in holoendemic settings. The relative contribution of immunity against various stages of the parasite life cycle that results in controlling infection and limiting disease is...

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Bibliographic Details
Main Authors: Mykola Pinkevych, Janka Petravic, Kiprotich Chelimo, James W Kazura, Ann M Moormann, Miles P Davenport
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3475668?pdf=render