Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome in podocytes has been implicated in the initiation of glomerular inflammation during hyperhomocysteinemia (hHcy). However, the mechanism by which NLRP3 inflammasome products are released from p...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Guangbi Li, Dandan Huang, Ningjun Li, Joseph K. Ritter, Pin-Lan Li
Format:	Artikel
Sprache:	English
Veröffentlicht:	Elsevier 2021-07-01
Schriftenreihe:	Redox Biology
Schlagworte:	Podocyte Homocysteine Reactive oxygen species TRPML1 channel Exosome Lysosome
Online Zugang:	http://www.sciencedirect.com/science/article/pii/S2213231721001713

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