Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome in podocytes has been implicated in the initiation of glomerular inflammation during hyperhomocysteinemia (hHcy). However, the mechanism by which NLRP3 inflammasome products are released from p...

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Bibliografische gegevens
Hoofdauteurs:	Guangbi Li, Dandan Huang, Ningjun Li, Joseph K. Ritter, Pin-Lan Li
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	Elsevier 2021-07-01
Reeks:	Redox Biology
Onderwerpen:	Podocyte Homocysteine Reactive oxygen species TRPML1 channel Exosome Lysosome
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2213231721001713

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