The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa

Abstract Glioblastoma multiforme (GBM) is the most common tumor of the human central nervous system. Aerobic glycolysis has been strongly related to tumor development and malignant behavior. In this study, we found that MBNL1, circNTRK2, and NTRK2-243aa were markedly downregulated and inhibited glyc...

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Bibliographic Details
Main Authors: Yubo Zhao, Jian Song, Weiwei Dong, Xiaobai Liu, Chunqing Yang, Di Wang, Yixue Xue, Xuelei Ruan, Libo Liu, Ping Wang, Mengyang Zhang, Yunhui Liu
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05219-4