Lyophilization to enable distribution of ChAdOx1 and ChAdOx2 adenovirus-vectored vaccines without refrigeration

Abstract Distribution of vaccines which require refrigerated or frozen storage can be challenging and expensive. The adenovirus vector platform has been widely used for COVID-19 vaccines while several further candidate vaccines using the platform are in clinical development. In current liquid formul...

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Bibliographic Details
Main Authors: Cheng Zhang, Adam Berg, Carina C. D. Joe, Paul A. Dalby, Alexander D. Douglas
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00674-2