The Role of Circulating Aβ Seeds in the Progression of Cerebral Amyloidosis

While understudied, it is suspected that peripheral Aβ peptides affect Alzheimer’s disease (AD)-associated pathological changes in the brain. The peripheral sink hypothesis postulates that the central and peripheral pools of Aβ co-exist in equilibrium. As such, cerebral amyloid levels may be modulat...

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Bibliographic Details
Main Authors: Nazaret Gamez, Rodrigo Morales
Format: Article
Language:English
Published: SAGE Publishing 2022-09-01
Series:Neuroscience Insights
Online Access:https://doi.org/10.1177/26331055221123072