Enhancing Human Immunodeficiency Virus-specific CD8+ T cell Responses with Heteroclitic Peptides

Human immunodeficiency virus (HIV)-specific CD8+ T cells play a critical role in containing HIV replication and delaying disease progression. However, HIV-specific CD8+ T cells become progressively more exhausted as chronic HIV infection proceeds. Symptoms of T cell exhaustion range from expression...

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Bibliographic Details
Main Authors: Adeolu eAdegoke, Michael David Grant
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00377/full