Enhancing Human Immunodeficiency Virus-specific CD8+ T cell Responses with Heteroclitic Peptides
Human immunodeficiency virus (HIV)-specific CD8+ T cells play a critical role in containing HIV replication and delaying disease progression. However, HIV-specific CD8+ T cells become progressively more exhausted as chronic HIV infection proceeds. Symptoms of T cell exhaustion range from expression...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-07-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00377/full |