Endothelin 3/EDNRB signaling induces thermogenic differentiation of white adipose tissue
Abstract Thermogenic adipose tissue, consisting of brown and beige fat, regulates nutrient utilization and energy metabolism. Human brown fat is relatively scarce and decreases with obesity and aging. Hence, inducing thermogenic differentiation of white fat offers an attractive way to enhance whole-...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-51579-0 |