Comprehensive Analysis of Cardiac Xeno-Graft Unveils Rejection Mechanisms

Comprehensive Analysis of Cardiac Xeno-Graft Unveils Rejection Mechanisms

Porcine heart xenotransplantation is a potential treatment for patients with end-stage heart failure. To understand molecular mechanisms of graft rejection after heart transplantation, we transplanted a 31-day-old <i>alpha-1,3-galactosyltransferase knockout</i> (GTKO) porcine heart to a...

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Bibliographic Details
Main Authors: Min Young Park, Bala Murali Krishna Vasamsetti, Wan Seop Kim, Hee Jung Kang, Do-Young Kim, Byeonghwi Lim, Kahee Cho, Jun Seok Kim, Hyun Keun Chee, Jung Hwan Park, Hyun Suk Yang, Harikrishna Reddy Rallabandi, Sun A. Ock, Mi-Ryung Park, Heasun Lee, In-Sul Hwang, Jun-Mo Kim, Keon Bong Oh, Ik Jin Yun
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
porcine cardiac tissue
xenotransplantation
heart failure
transcriptome analysis (or RNA-seq analysis)
Online Access:https://www.mdpi.com/1422-0067/22/2/751

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https://www.mdpi.com/1422-0067/22/2/751

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