Coptisine Inhibits Influenza Virus Replication by Upregulating p21

The activation of innate antiviral immunity is a promising approach for combatting viral infections. In this study, we screened Chinese herbs that activated human immunity and identified coptisine as a potent inhibitor of the influenza virus with an EC<sub>50</sub> of 10.7 μM in MDCK cel...

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Bibliographic Details
Main Authors: Ming-Feng He, Jian-Hui Liang, Yan-Ni Shen, Chao-Wei Zhang, Kuang-Yang Yang, Li-Chu Liu, Qian Xie, Chun Hu, Xun Song, Yan Wang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/14/5398