Fast-acting and injectable cryoneurolysis device
Abstract Cryoneurolysis is an opioid-sparing therapy for long-lasting and reversible reduction of pain. We developed a nerve-selective method for cryoneurolysis by local injection of ice-slurry (− 5 to − 6 °C) that induced decrease in nocifensive response starting from about a week after treatment a...
Main Authors: | Sara Moradi Tuchayi, Ying Wang, Alla Khodorova, Isaac J. Pence, Anat Stemmer-Rachamimov, Conor L. Evans, R. Rox Anderson, Lilit Garibyan |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-24178-6 |
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