Terminalin from African Mango (<i>Irvingia gabonensis</i>) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases

Terminalin from African Mango (<i>Irvingia gabonensis</i>) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases

Protein tyrosine phosphatases (PTPs), along with protein tyrosine kinases, control signaling pathways involved in cell growth, metabolism, differentiation, proliferation, and survival. Several PTPs, such as PTPN1, PTPN2, PTPN9, PTPN11, PTPRS, and DUSP9, disrupt insulin signaling and trigger type 2 d...

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Bibliographic Details
Main Authors: Sun-Young Yoon, Jinsoo Kim, Bum Soo Lee, Su Cheol Baek, Sang J. Chung, Ki Hyun Kim
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomolecules
Subjects:
protein tyrosine phosphatases (PTPs)
PTPN1
PTPN9
PTPN11
PTPRS
type 2 diabetes
Online Access:https://www.mdpi.com/2218-273X/12/2/321

Internet

https://www.mdpi.com/2218-273X/12/2/321

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