Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma
Glioblastoma (GBM) is the most malignant and aggressive form of glioma and is associated with a poor survival rate. Latest generation Tumour Necrosis Factor Related Apoptosis-Inducing Ligand (TRAIL)-based therapeutics potently induce apoptosis in cancer cells, including GBM cells, by binding to deat...
Egile Nagusiak: | , , , , , , |
---|---|
Formatua: | Artikulua |
Hizkuntza: | English |
Argitaratua: |
MDPI AG
2021-12-01
|
Saila: | Molecules |
Gaiak: | |
Sarrera elektronikoa: | https://www.mdpi.com/1420-3049/26/24/7582 |