Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of Paenibacillus thiaminolyticus

Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of Paenibacillus thiaminolyticus

ABSTRACT Hydrocephalus, the leading indication for childhood neurosurgery worldwide, is particularly prevalent in low- and middle-income countries. Hydrocephalus preceded by an infection, or postinfectious hydrocephalus, accounts for up to 60% of hydrocephalus in these areas. Since many children wit...

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Bibliographic Details
Main Authors: Christine Hehnly, Aiqin Shi, Paddy Ssentongo, Lijun Zhang, Albert Isaacs, Sarah U. Morton, Nicholas Streck, Petra Erdmann-Gilmore, Igor Tolstoy, R. Reid Townsend, David D. Limbrick, Joseph N. Paulson, Jessica E. Ericson, Michael Y. Galperin, Steven J. Schiff, James R. Broach
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
Paenibacillus thiaminolyticus
postinfectious hydrocephalus
type IV pilus
virulence factors
Online Access:https://journals.asm.org/doi/10.1128/mbio.02688-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02688-22

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