PEGylated Recombinant Human Hyaluronidase (PEGPH20): transition from a novel functional excipient to an API to increase the chemotherapeutic effectiveness against hyaluronan-rich cancers.
rHuPH20 is a novel new functional excipient that can increase SC drug volume, thus facilitating change over from the invasive IV to the more benign SC route. Its PEGylated analog, PEGPH20, using the same mechanism of action as rHuPH20, has shown; and continues to show; promising results when combine...
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| Format: | Article |
| Language: | English |
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International Pharmaceutical Excipients Council
2018-03-01
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| Series: | Journal of Excipients and Food Chemicals |
| Online Access: | https://jefc.scholasticahq.com/article/3407-pegylated-recombinant-human-hyaluronidase-pegph20-transition-from-a-novel-functional-excipient-to-an-api-to-increase-the-chemotherapeutic-effective |