S1P/S1PR1 signaling is involved in the development of nociceptive pain

BackgroundPain is a complex perception involving unpleasant somatosensory and emotional experiences. However, the underlying mechanisms that mediate its different components remain unclear. Sphingosine-1-phosphate (S1P), a metabolite of sphingomyelin and a potent lipid mediator, initiates signaling...

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Bibliographic Details
Main Authors: Daosong Dong, Xue Yu, Xueshu Tao, Qian Wang, Lin Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1407347/full