3-Nitroindoles Serving as <i>N</i>-Centered Nucleophiles for Aza-1,6-Michael Addition to <i>para</i>-Quinone Methides

3-Nitroindoles Serving as <i>N</i>-Centered Nucleophiles for Aza-1,6-Michael Addition to <i>para</i>-Quinone Methides

An unprecedented <i>N</i>-alkylation of 3-nitroindoles with <i>para</i>-quinone methides was developed for the first time. Using potassium carbonate as the base, a wide range of structurally diverse <i>N</i>-diarylmethylindole derivatives were obtained with modera...

Full description

Bibliographic Details
Main Authors: Jian-Qiang Zhao, Wen-Jie Wang, Shun Zhou, Qi-Lin Xiao, Xi-Sha Xue, Yan-Ping Zhang, Yong You, Zhen-Hua Wang, Wei-Cheng Yuan
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
3-nitroindoles
<i>N</i>-alkylation
<i>para</i>-quinone methides
<i>aza</i>-1,6-Michael addition
indole derivatives
Online Access:https://www.mdpi.com/1420-3049/28/14/5529

Internet

https://www.mdpi.com/1420-3049/28/14/5529

Similar Items